There are two possibilities to submit samples to CZ-OPENSCREEN.

1. Solution (preferential)
   1. All compounds should be submitted as solutions in DMSO. Samples which cannot be dissolved in DMSO, can be optionally dissolved in H2O.
   2. Concetration of the solution should be 10 mmol/L (i.e. 0.01 mol/L)
   3. Volume of the solution should be 250 - 1000 µL.
   4. Samples must be placed in 96-format Thermo Matrix™ 1.0mL ScrewTop 2D-barcoded Tubes. (www.thermoscientific.com/en/product/matrix-screw-caps-screw-cap-trays.html, catalog number: 3741). Racks with tubes will be provided.
   5. The last column of the rack (i.e. tubes with coordinates A12-H12) must be left empty (i.e. there can be max 88 samples per rack).
   6. Acceptable DMSO: Sigma-Aldrich 41640 (DMSO puriss. p.a., ACS reagent http://sigmaaldrich.com).
2. Solid (for number of samples less than 50)
   1. The amount of the sample (placed in a properly labeled glass vial) should be around 1 mg (weighted exactly with precission 0.1 mg), so that after dissolving in 250-1000 µl of DMSO, the concentration will be 10 mmol/L.

Information about the samples (structures and/or molecular weight, concentration, plate position, ...) must be submitted in the recommended format. recommended format.